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Abstract Spatial adjustments are used to improve the estimate of plot seed yield across crops and geographies. Moving means (MM) and P‐Spline are examples of spatial adjustment methods used in plant breeding trials to deal with field heterogeneity. Within the trial, spatial variability primarily comes from soil feature gradients, such as nutrients, but a study of the importance of various soil factors including nutrients is lacking. We analyzed plant breeding progeny row (PR) and preliminary yield trial (PYT) data of a public soybean breeding program across 3 years consisting of 43,545 plots. We compared several spatial adjustment methods: unadjusted (as a control), MM adjustment, P‐spline adjustment, and a machine learning‐based method called XGBoost. XGBoost modeled soil features at: (a) the local field scale for each generation and per year, and (b) all inclusive field scale spanning all generations and years. We report the usefulness of spatial adjustments at both PR and PYT stages of field testing and additionally provide ways to utilize interpretability insights of soil features in spatial adjustments. Our work shows that using soil features for spatial adjustments increased the relative efficiency by 81%, reduced the similarity of selection by 30%, and reduced the Moran's I from 0.13 to 0.01 on average across all experiments. These results empower breeders to further refine selection criteria to make more accurate selections and select for macro‐ and micro‐nutrients stress tolerance.